Posts Tagged ‘mTOR’:

Drugging the PI3 kinome: from chemical tools to drugs in the clinic

Workman P, Clarke PA, Raynaud F “Cancer research” 2010 The phosphatidylinositide 3-kinase (PI3K) pathway is rather commonly activated in a wide array of human cancersand is particularly a serious motivator in oncogenesis. One of several class I lipid kinase people in the PI3K family, p110alpha, has become the most commonly mutated kinasewithin the human genome.

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