Posts Tagged ‘epidermal growth factor receptor inhibition (EGFR)’:

Mitogen-activated protein/extracellular signal-regulated kinase

Schad K, Baumann Conzett K, Zipser M “Clinical cancer research 2010″ PURPOSE: Raf/mitogen-activated protein/extracellular signal-regulated kinase (ERK) kinase (MEK)/ERK signaling pathway is constitutively activated in melanoma. AZD6244 blocks MEK1/2, inhibiting ERK phosphorylation. We focus on associated cutaneous toxicity and we attempt to understand the underlying pathophysiology and design treatment strategies. EXPERIMENTAL DESIGN: Dermatologic conditions of

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© Apoptosis|apoptosis inhibitor|apoptosis pathway