Posts Tagged ‘cancer stem cells (CSCs)’:

Targeting Epigenetic Regulation of miR-34a for Treatment of Pancreatic Cancer by Inhibition of Pancreatic Cancer Stem Cells

Nalls D, Tang SN, Rodova M, Srivastava RK, Shankar S. “PLoS 1. 2011 Aug” BACKGROUND: MicroRNA-34a (miR-34a) can be a transcriptional target of p53 and it is down-regulated in pancreatic cancer. This research aimed to research the functional significance of miR-34a in pancreatic cancer progression via its epigenetic restoration with chromatin modulators, demethylating agent 5-Aza-2′-deoxycytidine

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