Fgfr signaling for the treatment of benign prostatic hyperplasia is licensed

The continuity t of the vessel E in the vascular Ren anatomy of the normal prostate and prostate disease. The treatment of h H depends Mospermie Aetiological causes. In this study, the H Mospermie idiopathic Etiology h Ufigsten found in 24 patients of 70 patients. Finasteride was approved fgfr signaling by the FDA for the management of BPH. Finasteride inhibits the conversion of testosterone to dihydrotestosterone, and for the treatment of benign prostatic hyperplasia is licensed. It is also used to H Maturie the prostate to treat origin. Although finasteride, unwanted side effects such as abdominal pain, can cause back pain, decreased libido and decreased volume of ejaculate. We do not have these side effects in our 12 patients who fulfilled again U is the drug, and this may be D Improvement in the psyche of the patient to improve their symptoms H mospermie Me and because of the relatively young age.
However, two patients reported decreased libido, which improved after discontinuing the drug. Our results on the effect of finasteride in patients MLN518 with idiopathic H Mospermie seem to show a clear statistically significant positive effect than placebo 66% vs. 25% 0.05 P value. The m Possible mechanism of the effects of finasteride on the bleeding k Ren can be explained, That finasteride blocks the conversion of testosterone to dihydrotestosterone, which decreased to an activity t contr growth factors Lee of androgens responsible for angiogenesis, resulting in decreased angiogenesis and thus reduces the blood supply to the prostate.
New data now show that patients with clinical BPH and recurrent maturie Makroh A density of Microvascular E suburethral prostate distinctly To have her alone in patients with BPH. VEGF, a strong promoter of angiogenesis, in patients treated with finasteride can be reduced. However, the recent data confirm Reduce that finasteride, a 5a-reductase inhibitor, an effective means of treatment of H. Maturie in these patients and bleeding in persons in BPH-related surgery. However, some questions remain open. What is the optimal dose in these patients and how long they should be treated In our study, all M Men in the finasteride group treated for 3 months and the drug was then discontinued. After the drug was withdrawn, had two of 12 patients recurrent H Mospermie. Our series is a pilot study should be considered.
The n HIGHEST step is to develop a broader and more controlled study Controlled by placebo, our best results to embarkation. BPH is an hour INDICATIVE disease in aging M Nnern histologically by hyperplastic dumplings tchen in the region marked periurethral and transition zone of the prostate or prostate cancer of a clinically palpable enlarged Ert and LUTS. Be the mounting evidence that infl ammation in BPH / LUTS development involved can k. In animal models was prostate induced infl ammation been shown to contribute to prostatic hyperplasia, and in humans, infl ammatory ltrates INFI be h Frequently in samples of prostate tissue by M Nnern with observed BPH and the presence or degree of infl ammation was found that correlated with prostate volume / weight, severity of LUTS and surgery for acute urinary retention independent ngig of urinary tract infections. Closing Lich, in a study of BPH / LUTS therapy, chronic infl ammation of the prostate with an increased Hten associated risk o

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