The level of oxidative stress as reflected by the nitrotyrosine content was augmented in SHR renal arteries, as were the expressions of NOX-2 and p67 phox , while the levels of SOD-1 and SOD-2 were diminished. Chronic treatment with calcitriol corrected the over-expression of NOX-2, p67 phox , and nitrotyrosine, and enhanced the expression of
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